3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

incazelo emfushane:

I-Chemical & Physical Properties

I-5-morpholin-4-yl-1- (4-nitrophenyl) -2,3-dihydropyridin-6-one isetshenziswa njengendawo ephakathi ye-apixaban.

I-Apixaban iyi-oral selective activation factor X inhibitor engavimbela i-thrombosis, kodwa imiphumela emibi yokopha iphansi kunaleyo ye-warfarin yezidakamizwa ezindala.Isetshenziselwa ukuvimbela i-thrombosis ezigulini eziye zahlinzwa ukuguqulwa kwe-hip noma idolo.

Uma unentshisekelo ngemikhiqizo yethu noma unemibuzo, sicela ukhululeke ukuxhumana nathi!

Imikhiqizo engaphansi kwelungelo lobunikazi inikezwa inhloso ye-R & D kuphela.

Ukubukeka :impushana emhlophe ukuya emhlophe

Isivivinyo :≥99.0%

Ukuminyana:1.357 g/cm3

Indawo yokubilisa:506.5℃ ku-760 mmHg

I-Flash Point:260.1℃

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo Yomkhiqizo

Igama Lomkhiqizo	5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone CAS NO:503615-03-0
Omqondofana	I-3-Morpholino-1- (4-nitrophenyl) -5,6-dihydropyridin-2 (1H) -enye;
I-CAS NO	503615-03-0
I-Molecular Formula	I-C15H17N3O4
Isisindo samangqamuzana	303.313
EINECS NO	N/A
I-MDL NO	N/A

Isicelo

Sebenzisa: I-apixaban intermediate ku-A

I-3- (Morpholinyl) -N- (4-nitrophenyl) -5,6-dihydropyridin-2-one i-reagent esetshenziselwa ukuhlanganiswa kwe-4,5-dehydro Apixaban (D229385), okuwukungcola kwe-Apixaban (A726700) , i-inhibitor enamandla, eqondile, ekhethiwe, futhi esebenzayo ngomlomo ye-coagulation factor Xa.Kuyi-ejenti yenoveli ye-oral coagulation engase isetshenziselwe ukuvimbela i-VTE ku-hip isiyonke, ukuhlinzwa kwamathambo esikhundleni samadolo, kanye nokwelapha isifo sohlangothi ezigulini ezinesifo se-venous thromboembolic noma i-atrial fibrillation.

Izinzuzo Zethu

1. Isampula yesevisi yokusungula esebenzayo, i-IATF 16946:2016 uhlelo lokulawula ikhwalithi.
2.Ithimba lesevisi ye-inthanethi elichwepheshile, noma iyiphi i-imeyili noma umlayezo uzophendula engakapheli amahora angama-24.
3. Sineqembu eliqinile, elilungele ukunikeza amakhasimende inkonzo yenhliziyo yonke.
4. Sinamathela kufilosofi yebhizinisi "yekhasimende kuqala, abasebenzi benjabulo".
5. Beka izinga njengelokuqala;
I-6.OEM, ODM, idizayini yangokwezifiso / uphawu/ uhlobo, ukupakishwa kuyatholakala.
7. Imishini yokukhiqiza ethuthukisiwe, uhlelo oluqinile lokulawula ikhwalithi, ukuqinisekisa ikhwalithi enhle kakhulu.
8. Intengo yokuncintisana: singabakhiqizi bezingxenye zezimoto abangochwepheshe e-China, akukho nzuzo yabaphakathi, ungathola kithi inani elincintisana kakhulu.
9. Ikhwalithi enhle: ikhwalithi enhle ingaqinisekiswa, izokusiza ukuthi uhlale unesabelo semakethe kahle.
10. Ukulethwa okusheshayo: sinefektri yethu kanye nabakhiqizi abangochwepheshe, kongela isikhathi nenkampani yohwebo ukuze uxoxisane.Sizozama konke okusemandleni ethu ukuhlangabezana nezidingo zakho.

2）
1. Imigomo Yokukhokha : DA izinsuku ezingu-90.TT In Advance L/C: Ngokubona
2.Umthamo Wezinyanga : 1MTS
3.Ulwazi lwangokwezifiso : NjengeKhasimende
4. Indlela Yokulayisha : Ngasolwandle, Ngomoya.
5.Ichweba lomkhumbi : Shang Hai .UNing Bo , Qingdao Tian Jing , Guangzhou .
6.Ulwazi lwephakheji: Njengefekthri noma Ngokwezifiso Zekhasimende.
7.Ulwazi lokuphepha : Izimpahla ezingezona eziyingozi

Okwedlule: 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

Olandelayo: 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone